NAD+ Optimization Protocol

This longevity protocol appears to target cellular health and potentially influence aging processes, primarily through compounds associated with energy metabolism and antioxidant activity. The inclusion of NMN and Resveratrol suggests a focus on pathways related to NAD+ production and sirtuin activation, both of which are implicated in cellular repair and longevity. These compounds are believed to support mitochondrial function, reduce oxidative stress, and promote overall cellular resilience.

The evidence base for this protocol is uneven. Resveratrol and NMN have the most research backing, with 13 and 11 findings respectively, suggesting a reasonable body of evidence exploring their potential benefits. However, Apigenin, Niacin, Nicotinamide Riboside, and TMG currently have very limited or no reported research findings. This lack of evidence doesn't necessarily negate their potential value, but it does highlight the need for further investigation to understand their effects and efficacy within a longevity context.